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Publications
Multimodal profiling reveals site-specific adaptation and tissue residency hallmarks of γδ T cells across organs in mice
Anastasia du Halgouet, Kerstin Bruder, Nina Peltokangas, Aurélie Darbois, David Obwegs, Marion Salou, Robert Thimme, Maike Hofmann, Olivier Lantz & Sagar
Endothelial TDP-43 controls sprouting angiogenesis and vascular barrier integrity, and its deletion triggers neuroinflammation
Víctor Arribas,Yara Onetti, Marina Ramiro-Pareta, Pilar Villacampa, Heike Beck, Mariona Alberola, Anna Esteve-Codina, Angelika Merkel, Markus Sperandio, Ofelia M. Martínez-Estrada, Bettina Schmid, and Eloi Montanez
Circadian Clock and Hypoxia
Francesca Sartor, Borja Ferrero-Bordera, Jeffrey Haspel, Markus Sperandio, Paul M Holloway, Martha Merrow
Early-life vitamin A treatment rescues neonatal infection-induced durably impaired tolerogenic properties of celiac lymph nodes
Mangge Zou, Joern Pezoldt, Juliane Mohr, Lars Philipsen, Andrea Leufgen, Vuk Cerovic, Carolin Wiechers, Marina Pils, Diego Ortiz, Lianxu Hao, Juhao Yang, Michael Beckstette, Aline Dupont, Mathias Hornef, Petra Dersch, Till Strowig, Andreas J. Müller, Jens Raila, Jochen Huehn
Circulating NK cells establish tissue residency upon acute infection of skin and mediate accelerated effector responses to secondary infection
Tommaso Torcellan, Christin Friedrich, Rémi Doucet-Ladevèze, Thomas Ossner, Virgínia Visaconill Solé, Sofie Riedmann, Milas Ugur, Fabian Imdahl, Stephan P. Rosshart, Sebastian J. Arnold, Mercedes Gomez de Agüero, Nicola Gagliani, Richard A. Flavell, Simone Backes, Wolfgang Kastenmüller, Georg Gasteiger
Unraveling the secrets of γδ T cells with single-cell biology
Endothelial TDP-43 controls sprouting angiogenesis and vascular barrier integrity, and its deletion triggers neuroinflammation
Víctor Arribas, Yara Onetti, Marina Ramiro-Pareta, Pilar Villacampa, Heike Beck, Mariona Alberola, Anna Esteve-Codina, Angelika Merkel, Markus Sperandio, Ofelia M. Martínez-Estrada, Bettina Schmid, and Eloi Montanez
Interleukin-10 enhances recruitment of immune cells in the neonatal mouse model of obstructive nephropathy
Maja Wyczanska, Franziska Thalmeier, Ursula Keller, Richard Klaus, Hamsa Narasimhan, Xingqi Ji, Barbara U. Schraml, Lou M. Wackerbarth & Bärbel Lange‑Sperandio
The niche matters: origin, function and fate of CNS-associated macrophages during health and disease
Adrià Dalmau Gasull, Martina Glavan, Sai K. Reddy Samawar, Kishan Kapupara, Joe Kelk, Marina Rubio, Stefano Fumagalli, Lydia Sorokin, Denis Vivien & Marco Prinz
Maternal rhythms suppress neonatal inflammation
Non-professional efferocytosis of Salmonella-infected intestinal epithelial cells in the neonatal host
Kaiyi Zhang, Urska Repnik, Nour Diab, Daniel Friske, Andreas Pütz, Alina Z. Bachmann, Narasimha Murthy Keshava Prasad Gubbi1, Michael Hensel, Konrad U. Förstner, Alexander J. Westermann, Aline Dupont, and Mathias W. Hornef
E-selectin-mediated rapid NLRP3 inflammasome activation regulates S100A8/S100A9 release from neutrophils via transient gasdermin D pore formation
Monika Pruenster, Roland Immler, Jonas Roth, Tim Kuchler, Thomas Bromberger, Matteo Napoli, Katrin Nussbaumer, Ina Rohwedder, Lou Martha Wackerbarth, Chiara Piantoni, Konstantin Hennis, Diana Fink, Sebastian Kallabis, Tobias Schroll, Sergi Masgrau-Alsina, Agnes Budke, Wang Liu, Dietmar Vestweber, Christian Wahl-Schott, Johannes Roth, Felix Meissner, Markus Moser, Thomas Vogl, Veit Hornung, Petr Broz & Markus Sperandio
Laboratory mice with a wild microbiota generate strong allergic immune responses
Ma J, Urgard E, Runge S, Classon CH, Mathä L, Stark JM, Cheng L, Álvarez JA, von Zedtwitz S, Baleviciute A, Martinez Hoyer S, Li M, Gernand AM, Osbelt L, Bielecka AA, Lesker TR, Huang HJ, Vrtala S, Boon L, Beyaert R, Adner M, Martinez Gonzalez I, Strowig T, Du J, Nylén S, Rosshart SP, Coquet JM.
Impact of High Salt-Intake on a Natural Gut Ecosystem in Wildling Mice
Cardilli A, Hamad I, Dyczko A, Thijs S, Vangronsveld J, Müller DN, Rosshart SP, Kleinewietfeld M.
Human resident liver myeloid cells protect against metabolic stress in obesity
Barreby E, Strunz B, Nock S, Naudet L, Shen JX, Johansson H, Sönnerborg I, Ma J, Urgard E, Pallett LJ, Hu Y, Fardellas A, Azzimato V, Vankova A, Levi L, Morgantini C, Maini MK, Stål P, Rosshart SP, Coquet JM, Nowak G, Näslund E, Lauschke VM, Ellis E, Björkström NK, Chen P, Aouadi M.
Neutrophils direct preexisting matrix to initiate repair in damaged tissues
Fischer A, Wannemacher J, Christ S, Koopmans T, Kadri S, Zhao J, Gouda M, Ye H, Mück-Häusl M, Krenn PW, Machens HG, Fässler R, Neumann PA, Hauck SM, Rinkevich Y.
Projects
Artikel
New paper from PILOT member Sagar
Unlocking the Intricacies of Gamma-Delta T Cells
Gamma-delta T cells represent a…
New paper from PILOT member Stephan Rosshart
A recent paper from a international team of scientists, including PILOT member Stephan Rosshart…
Events
***SPECIAL EVENT*** PILOT International Symposium on Perinatal and Early Life Immunity
PILOT will be hosting an International Symposium on Perinatal and Early Life Immunity from 9-12 April 2025 at the Historisches Kaufhaus in Freiburg
We already have a fantastic line-up of invited speakers for this event. We plan to complement this with talks selected on the basis of abstracts and there will also be opportunities to present posters.
More details will be posted here as they are finalized; in the meantime, please save the date!