Feb 24, 2025
New PILOT publication in PNAS
A new publication in PNAS - co-authored by 5 PILOT members - has shown that a particular...
Article
Jan 05, 2024
New paper from PILOT member Sagar
Unlocking the Intricacies of Gamma-Delta T Cells
Gamma-delta T cells represent a...
Jun 13, 2023
New paper from PILOT members Hornef, Clavel and Rosshart
PILOT members including Mathias Hornef, Tom Clavel and Stephan Rosshart have recently published...
Publications
RORγt-expressing dendritic cells are functionally versatile and evolutionarily conserved antigen-presenting cells
Hamsa Narasimhan, Maria L. Richter, Ramin Shakiba, Nikos E. Papaioannou, Christina Stehle, Kaushikk Ravi Rengarajan, Isabel Ulmert, Arek Kendirli, Clara de la Rosa, Pin-Yu Kuo, Abigail Altman, Philipp Münch, Saba Mahboubi, Vanessa Küntzel, Amina Sayed, Eva-Lena Stange, Jonas Pes, Alina Ulezko Antonova, Carlos-Filipe Pereira, Ludger Klein, Diana Dudziak, Marco Colonna, Natalia Torow, Mathias W. Hornef, Björn E. Clausen, Martin Kerschensteiner, Katharina Lahl, Chiara Romagnani, Maria Colomé-Tatché, and Barbara U. Schraml
2025 PNAS
Early-life vitamin A treatment rescues neonatal infection-induced durably impaired tolerogenic properties of celiac lymph nodes
Mangge Zou, Joern Pezoldt, Juliane Mohr, Lars Philipsen, Andrea Leufgen, Vuk Cerovic, Carolin Wiechers, Marina Pils, Diego Ortiz, Lianxu Hao, Juhao Yang, Michael Beckstette, Aline Dupont, Mathias Hornef, Petra Dersch, Till Strowig, Andreas J. Müller, Jens Raila, Jochen Huehn
2024 Cell Reports
Phase II trial of hypomethylating agent combined with nivolumab for acute myeloid leukaemia relapse after allogeneic haematopoietic cell transplantation—Immune signature correlates with response
Petya Apostolova, Stefanie Kreutmair, Cristina Toffalori, Marco Punta, Susanne Unger, Ann-Cathrin Burk, Claudia Wehr, Kristina Maas-Bauer, Wolfgang Melchinger, Eileen Haring, Rouven Hoefflin, Khalid Shoumariyeh, Valerie Hupfer, Eliza Maria Lauer, Sandra Duquesne, Theresa Lowinus, Nicolás Gonzalo Núñez, Chiara Alberti, Sara da Costa Pereira, Carla Helena Merten, Laura Power, Matthias Weiss, Caroline Böke, Dietmar Pfeifer, Reinhard Marks, Hartmut Bertz, Ralph Wäsch, Gabriele Ihorst, Bernhard Gentner, Justus Duyster, Melanie Boerries, Geoffroy Andrieux, Juergen Finke, Burkhard Becher, Luca Vago, Robert Zeiser
2023 British Journal of Haematology
Unraveling the secrets of γδ T cells with single-cell biology
2024 Journal of Leukocyte Biology
Interleukin-10 enhances recruitment of immune cells in the neonatal mouse model of obstructive nephropathy
Maja Wyczanska, Franziska Thalmeier, Ursula Keller, Richard Klaus, Hamsa Narasimhan, Xingqi Ji, Barbara U. Schraml, Lou M. Wackerbarth & Bärbel Lange‑Sperandio
2024 Scientific Reports
Multimodal profiling reveals site-specific adaptation and tissue residency hallmarks of γδ T cells across organs in mice
Anastasia du Halgouet, Kerstin Bruder, Nina Peltokangas, Aurélie Darbois, David Obwegs, Marion Salou, Robert Thimme, Maike Hofmann, Olivier Lantz & Sagar
2024 Nature Immunology
Postnatal expansion of mesenteric lymph node stromal cells towards reticular and CD34+ stromal cell subsets
Pezoldt J, Wiechers C, Zou M, Litovchenko M, Biocanin M, Beckstette M, Sitnik K, Palatella M, van Mierlo G, Chen W, Gardeux V, Floess S, Ebel M, Russeil J, Arampatzi P, Vafardanejad E, Saliba AE, Deplancke B, Huehn J.
2022 Nat Commun
M cell maturation and cDC activation determine the onset of adaptive immune priming in the neonatal Peyer’s patch
Torow N, Li R, Hitch TCA, Mingels C, Al Bounny S, van Best N, Stange EL, Simons B, Maié T, Rüttger L, Gubbi NMKP, Abbott DA, Benabid A, Gadermayr M, Runge S, Treichel N, Merhof D, Rosshart SP, Jehmlich N, Hand TW, von Bergen M, Heymann F, Pabst O, Clavel T, Tacke F, Lelouard H, Costa IG, Hornef MW
2023 Immunity
Events
***SPECIAL EVENT*** PILOT International Symposium on Perinatal and Early Life Immunity
PILOT will be hosting an International Symposium on Perinatal and Early Life Immunity from 9-12 April 2025 at the Historisches Kaufhaus in Freiburg
We already have a fantastic line-up of invited speakers for this event. We plan to complement this with talks selected on the basis of abstracts and there will also be opportunities to present posters.
More details will be posted here as they are finalized; in the meantime, please save the date!